Formation of DNA Damaging Product from Light-Irradiated Nonylphenol
نویسندگان
چکیده
منابع مشابه
DNA Damaging Drugs
DNA damaging drugs interfere with transcription and reduplication. Affected cells respond with cell cycle arrest or programmed cell death. DNA damaging drugs are mutagenic, teratogenic, and carcinogenic. Adverse effects are exerted on rapidly proliferating cells (skin—hair loss, gastrointestinal tract—nausea and vomiting, bone marrow—anemia causing fatigue/leukopenia causing infections/thromboc...
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PURPOSE To evaluate the protective effects of midkine (MK), the product of a retinoic acid-responsive gene, on constant light-induced retinal degeneration in albino Sprague-Dawley rats. METHODS Midkine, basic fibroblast growth factor (bFGF), MK plus heparin, or buffer controls were injected intravitreally 2 days before constant light exposure. After 7 days of continuous light exposure, the ey...
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Cells from patients with the hereditary disorder Cockayne's syndrome and from the sun-sensitive individual, 11961, are sensitive to the lethal effects of ultraviolet light (UV) but have no detectable defect in either excision- or postreplication repair after UV irradiation. In normal cells and in Cockayne heterozygotes, UV causes a depression in the rate of DNA-replicative synthesis followed by...
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Background: The total yields of direct Single-Strand Breaks (SSBs) and Double-Strand Breaks (DSBs) in proton energies varying from 0.1 to 40 MeV were calculated. While other studies in this field have not used protons with energy less than 0.5 MeV, our results show interesting and complicated behavior of these protons. Materials and Methods: The simulation has been done using the Geant4-DNA too...
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ژورنال
عنوان ژورنال: Journal of Health Science
سال: 2006
ISSN: 1344-9702,1347-5207
DOI: 10.1248/jhs.52.91